Boeing's 747-8 freighter is nearing a half-year in service with 14 aircraft in service with five airlines.
The airframer says it has met or exceeded its expectations for in service reliability, fuel burn and payload capacity since its October 2011 first delivery to Cargolux.
In addition to the Luxembourg-based cargo hauler, 747-8F carriers include Cathay Pacific Cargo, AirBridgeCargo, Korean Air Cargo and Atlas Air for British Airways World Cargo.
The General Electric GEnx-2B-powered freighter is now approved to operate at 200 airports worldwide, the latest being London's Heathrow Airport.
Individual airport approval was required with the aircraft's 68.4m (224.4ft) wingspan compared to the 747-400, which placed the new freighter in the International Civil Aviation Organisation (ICAO) airport design code F criteria, which stretches from 65m (213.3ft) to 80m (262.5ft).