Aeromexico will operate its one-stop Boeing 787 service between Mexico City and Tokyo Narita via Monterrey from September, replacing the stop in Tijuana.
The airline operates four times weekly to Tokyo.
The switch to a Monterrey stop reinforces the importance of its new hub in Monterrey, says Aeromexico chief executive Andres Conesa in an earnings call today.
The SkyTeam carrier will add five new destinations from Monterrey - San Luis Potosi, Aguascalientes, Cancun, Puerto Vallarta and Los Cabos. It will also boost frequencies on existing routes to Leon, Chihuahua and Queretaro.
Aeromexico also added a fourth connecting bank of flights at Monterrey, and will serve 19 destinations from the city, says Conesa.