American Airlines will end its daily flight between Boston and London Heathrow on 31 March.
The Fort Worth-based Oneworld Alliance member's partner British Airways (BA) will replace the flight by adding a fourth daily frequency between the cities from 1 April 2013, according to the UK flag carrier.
American flies a 187-seat Boeing 757-200 on the route while BA flies a combination of 245-seat Boeing 777-200s and 319-seat Boeing 747-400s, according to Innovata schedules.
BA says that it has not selected an aircraft for the flight.
American and BA operate a metal neutral joint venture between the USA and UK.
Delta Air Lines and Virgin Atlantic Airways also fly between Boston and Heathrow, Innovata shows.