Cambodian airline Angkor Air will commence a daily service between Siem Reap and Bangkok's Suvarnabhumi International Airport from 30 November.
The carrier will use an ATR 72-500, configured with 67 seats, on the route.
Angkor Air, which began operations in 2010, is a joint venture between Vietnam Airlines and the Cambodian government. It flies domestically between Siem Reap, Phnom Penh and Sihanoukville, and internationally to Ho Chi Minh City.
The airline operates two Airbus A321s and two ATR 72-500s.