EasyJet will use London Gatwick slots acquired from Flybe to launch new routes to Brussels and Strasbourg.
From 30 March, the UK low-cost carrier will serve the Belgian capital twice-daily from Gatwick, and the French city four times weekly.
The new services are intended to extend EasyJet's reach among business travellers.
Luton-based EasyJet has already confirmed that Gatwick slots acquired from Flybe will be used for new services to Jersey, Newcastle and Paris Charles de Gaulle. It is also increasing frequencies to Amsterdam, Bordeaux, Geneva, Inverness and the Isle of Man. Overall, it expects its Gatwick expansion to create a need for 200 new crew members, split between pilots and cabin attendants.