Indonesian carrier Sky Aviation began its daily Batam Hang Nadim-Palembang Sultan Badaruddin II service on 10 October.
Sky says it expects to carry up to 15,000 passengers per month.
The carrier has one Fokker 100 aircraft, five Fokker 50 aircraft and one Boeing 737-300 aircraft that are available for passenger services.
The airline received its 737-300 in August. The aircraft, which can seat 138 passengers including eight in business class, has primarily been used to serve various domestic points in Indonesia from Jakarta.
Sky provides regular charter flights from Jakarta to the Riau islands using its Fokker 50 aircraft, as well as services to other Indonesian cities.
The airline has ordered 12 Sukhoi Superjet regional aircraft and is scheduled to receive the first of the type this year.