KLM is to replace its existing five-weekly Ecuador service via Bonaire with thrice-weekly nonstop flights to Quito and Guayaquil.
The carrier says it will serve the two destinations using Boeing 777-300 aircraft from 30 October.
On the same date, the Dutch carrier will increase frequencies to Caribbean destinations as part of its winter schedule.
KLM will increase its Amsterdam Schiphol-Curaçao service to nine times a week and its Bonaire route to daily. It will also boost frequencies from Schiphol to Aruba and St Maarten to five-times-weekly and thrice-weekly, respectively.
The flights to the Caribbean will use Boeing 747-400s and MD-11s, says the SkyTeam carrier.
According to the Innovata schedules, no other airline currently operates nonstop service from Amsterdam to the Ecuadorian cities of Quito and Guayaquil.