US Airways Express carrier Piedmont Airlines reached a tentative agreement with its pilots, represented by the Air Line Pilots Association.
The 375 pilots will have an opportunity to vote on the contract language in coming weeks after language is finalised.
In August, the pilots voted overwhelmingly to authorise a strike after being in negotiations for more than three years.
"We are very pleased that Piedmont and ALPA, with the assistance of the National Mediation Board, have reached a tentative agreement on a contract for our pilots," said Steve Farrow, Piedmont Airlines' chief executive. "This is a significant step toward reaching a new collective bargaining agreement" he said.
Piedmont's flight attendants represented by the Association of Flight Attendants-CWA (AFA) have also authorised to strike and requested a proffer of arbitration from the National Mediation Board in October.