Tiger Airways Australia plans to resume its Melbourne-Adelaide service on 1 November.
The low-cost carrier will operate twice daily flights from Melbourne's Tullamarine airport to Adelaide airport. The service will start in time for the summer holiday and upcoming new year festival season in south Australia.
Flights to and from Adelaide are still subject to regulatory approval, the carrier said in a statement.
"Tiger Airways is continuing with its Australian expansion as planned and our return to Adelaide is an important milestone on this journey," the airline's chief executive Andrew David, said in a statement.