Airbus has informed Japanese carrier Skymark Airlines that its order for six A380s has been terminated.
The airframer says it has taken the action "in accordance with its contractual rights".
Skymark had already disclosed that it was discussing with Airbus a possible cancellation of the 2011 order.
But Airbus says that, "in light of [Skymark's] expressed intentions" in respect of the A380, it has "notified" the airline that the purchase order for the six aircraft "has been terminated".
Airbus adds that it is "reserving all its rights and remedies".
Skymark had said that increased competition and weaker local currency had affected the business climate since the carrier placed the order.
But it had also expressed concern that the carrier would incur a large penalty if the order was cancelled. Skymark's Rolls-Royce Trent 900-powered aircraft are already in production with an initial airframe having flown.