Israeli flag-carrier El Al is to open its own nonstop services to San Francisco before the end of this year.
El Al says the Tel Aviv-San Francisco route will be operated by Boeing 787s.
The airline will commence the service in the fourth quarter of this year and fly the route three-times weekly.
It already offers San Francisco flights through a codeshare partnership with US carrier JetBlue Airways, while the route from Tel Aviv is also flown nonstop by Star Alliance carrier United Airlines with 787s.
El Al's new route will take to six the number of cities it serves in North America, including New York – the carrier operates to both JFK and Newark – Boston, Miami, Los Angeles and Toronto.
Outgoing chief executive David Maimon says San Francisco holds "strategic importance" for the airline, with "great emphasis" on business travel.