Qantas Airways will drop its daily Melbourne-Dubai-London route in March 2018 when it launches daily Melbourne-Perth-London service.
The Oneworld carrier detailed the network change in its announcement that tickets for the Perth-London route have gone on sale.
The Melbourne-Dubai-London route is served by Airbus A380 aircraft, while it will use the Boeing 787-9 aircraft on the new routing.
Qantas passengers in Melbourne will still have the option of flying on a Qantas code to Dubai with its partner airline, Emirates.
From 25 March 2018, Emirates will upgauge its third daily Melbourne-Dubai service from a Boeing 777-300ER to an A380.
By dropping the Melbourne-Dubai-London routing, Qantas frees up an A380 aircraft. This will be deployed during high demand periods from Melbourne and Sydney to cities in Asia such as Singapore and Hong Kong.
"The travel experience for customers connecting in Perth will be seamless, with Qantas building a new international transit lounge at Perth Airport," adds the carrier.
"People joining the flight to London from other parts of Australia (including regional Western Australia and Adelaide) will find it a smooth transition with international and domestic flights arriving and departing from the same terminal, complete with dedicated customs and immigration."